Low-dose sessions
Often a sublingual lozenge or low IM dose. More conversational; you usually stay present.
May suit people who
- Want to stay talkative and present
- Prefer a lighter format to start
- Like talking things through as they come up
Compare the two paths
Low-dose vs. high-dose ketamine
Two ways ketamine may be offered for depression and anxiety, side by side.
General education, not medical advice. No doses here: I'm a trained facilitator, not a therapist or medical provider, and a licensed provider decides the path, route, and dose.
At a glance
Two ways in, same careful process.
Both include preparation and integration with me. Licensed medical partners handle everything medical.
High-dose sessions
An IM injection at a higher dose. Deeper and more inward, with less talking.
May suit people who
- Want a more inward experience
- Are comfortable setting conversation aside
- Want more time for integration afterward
Side by side
How they generally compare.
| Topic | Path ALow dose | Path BHigh dose |
|---|---|---|
| Purpose | A gentler, conversational format: stay present enough to talk about what comes up. | A deeper, inward format: step back from everyday thinking, with talking saved for before and after. |
| How it may feel | Relaxed, floaty, or slightly detached, while staying aware and able to talk. Sounds or time may feel different. 2 | Strongly dissociative: dream-like or out-of-body, with less sense of surroundings or time. Can feel intense; it's temporary. 1,2 |
| Setting | A quiet room, sitting up or reclining. Often a sublingual lozenge or a low intramuscular (IM) injection. | A quiet, dim room, lying down, often with an eye mask and music. An intramuscular (IM) injection. |
| Session shape |
|
|
| Talking | Back-and-forth as things come up. | Very little during the deepest part. |
| May suit people who | Want to stay talkative and present, or prefer a lighter format to start. | Want a more inward experience, or more time set aside for integration. |
| What I do | Preparation; conversational support on session day, within what the medical partnership allows; integration. | Preparation, including letting go of control; a quiet, steady presence on session day, within what the medical partnership allows; integration. |
| What the medical team does | Screening; deciding the path, route, and dose; giving the medicine; monitoring until you're cleared to leave. | Screening; deciding the path, route, and dose; giving the injection; monitoring until you're cleared to leave. |
General descriptions, not predictions. If something feels physically wrong, tell the medical team right away. Step by step: what to expect before, during and after.
Either way
What's the same
- Screening comes first. A licensed provider reviews your health history and medications. 2
- The medical team gives and monitors the medicine. Ketamine is a prescription controlled substance. 1,2
- You need a ride home and a clear rest of the day. 2
- Preparation and integration with me are part of both paths.
- You can change your mind at any point before a session.
- No guaranteed outcomes. Research suggests ketamine may help some people; results vary. 2
A licensed medical provider decides which path, if any, is right for you. I don't recommend doses or routes. Ketamine isn't right for everyone, and the FDA has cautioned about unmonitored at-home use. 2,3 More on who decides whether ketamine is appropriate.
Not sure which fits?
Start with a free 15-minute intro call.
FAQ
Common questions.
Is high dose better than low dose?
Different, not better. Neither is right for everyone. Which one, if either, fits you is a medical decision made with a licensed provider after screening.
Can I choose which path?
Share your preference and why; that's a good thing to explore in preparation. The final call on the path, route, and dose belongs to your licensed medical provider.
Do you recommend doses or routes?
No. I don't recommend, prescribe, or give any medication. Licensed medical partners handle screening, prescribing, dosing, administration, and monitoring.
Is preparation different for each path?
The structure is the same: preparation before, integration after. High-dose preparation often spends more time on letting go of control, and people sometimes want more integration time afterward. More on integration.
What does it cost?
Pricing is shared on the free intro call. Medical services come from licensed medical partners and aren't part of Off Weekend's pricing.
Sources
- Rosenbaum SB, Gupta V, Patel P, et al. “Ketamine.” StatPearls, NCBI Bookshelf, U.S. National Library of Medicine.
- Cleveland Clinic. “Ketamine Therapy: What It Is, How It Works & Side Effects.” Medically reviewed January 16, 2026.
- U.S. Food and Drug Administration. “FDA warns patients and health care providers about potential risks associated with compounded ketamine products, including oral formulations, for the treatment of psychiatric disorders.” October 10, 2023. Listed under FDA Compounding Risk Alerts.
Start with a free intro call.
A free 15-minute phone call. Pick a time and I'll call you. No health questions, no pressure.
Book a free 15-min intro callPrefer email? [email protected]